Preventing Surgical-Site Infections in Nasal Carriers ofStaphylococcus aureus

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Preventing surgical-site infections in nasal carriers of Staphylococcus aureus.

BACKGROUND Nasal carriers of Staphylococcus aureus are at increased risk for health care-associated infections with this organism. Decolonization of nasal and extranasal sites on hospital admission may reduce this risk. METHODS In a randomized, double-blind, placebo-controlled, multicenter trial, we assessed whether rapid identification of S. aureus nasal carriers by means of a real-time poly...

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Preventing surgical site infections.

Over the past 50 years, increased interest in the discipline of surgical infection has resulted in advances in post-surgical infection control. Early investigations focused on the importance of anaerobic microflora to postoperative infection and paved the way for significant improvements in prophylactic and therapeutic antibiotic treatment of surgical patients. Later research centered on the id...

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Preventing surgical site infections: a surgeon's perspective.

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Back to basics: preventing surgical site infections.

A surgical site infection (SSI) is an unintended and oftentimes preventable consequence of surgery. There is a significant amount of literature related to preventing SSIs, and it is up to practitioners in each care setting to review the evidence and work together to implement SSI prevention measures, such as nasal decolonization, antibiotic prophylaxis, preoperative showers, preoperative oxygen...

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Preventing surgical site infections: a randomized, open-label trial of nasal mupirocin ointment and nasal povidone-iodine solution.

BACKGROUND Treatment of Staphylococcus aureus colonization before surgery reduces risk of surgical site infection (SSI). The regimen of nasal mupirocin ointment and topical chlorhexidine gluconate is effective, but cost and patient compliance may be a barrier. Nasal povidone-iodine solution may provide an alternative to mupirocin. METHODS We conducted an investigator-initiated, open-label, ra...

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ژورنال

عنوان ژورنال: New England Journal of Medicine

سال: 2010

ISSN: 0028-4793,1533-4406

DOI: 10.1056/nejmoa0808939